Menopause: blood test determines early menopause

Menopause: blood test determines early menopause

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Is menopause predictable?

Researchers from the USA tested the ability of a blood test for the so-called anti-Müllerian hormone (AMH) to predict when a woman will have her last period. The hormone is produced in the ovaries. If the AMH values ​​fall very low, this indicates that your ovaries have almost no functional eggs and your period will soon be absent.

A research team from several US institutions improved a blood test to predict a woman's last period and hence the onset of menopause. Older AMH tests have so far not been accurate enough to detect low values. The research results were published in the "Journal of Clinical Endocrinology and Metabolism (JCEM)".

Recognize menopause two to three years in advance

The researchers tested 1,537 women between the ages of 42 and 52 who were not yet going through the menopause with the new AMH test. The participants were observed until after their last period. It was shown that the new test was more accurate than previous methods, so that it could be predicted whether the menstrual period would end within the next two to three years.

The exact time cannot be determined

British media reports said the test could predict menopause two years in advance. However, the British National Health Service (NHS) stressed that this could be misunderstood. While the test can predict the likelihood that women of different ages will go into menopause in the next one to three years, it cannot be predicted exactly when.

Test shows probabilities

According to the researchers, a low AMH value in the blood (below 10pg / ml) is an indication of the impending menopause. The older the tested woman is, the more precisely the probability can be determined. The following overview shows the likelihood that menopause will set in next year with a low AMH value:

  • 51 percent chance of women under 48 years of age,
  • 63% probability in women between 48 and 51 years,
  • 79 percent chance of women aged 52 and over.

Test also works the other way around

According to the study, a high AMH value (more than 100pg / ml) is again a strong indication that a woman will not have her last period next year. For example, women who were over 52 and had high AMH levels had a 90 percent chance that their period would not fail in the next year. In women under 48, the probability is even 97 percent.

AMH measurement can help with treatment decisions

The researchers concluded that AMH measurements help women predict when vasomotor symptoms, such as hot flashes, are likely to start or when heavy menstrual bleeding and menstrual pain are likely to end. This could also have an impact on whether or not menstrual complaints should be treated.

Young women were not included

The research team indicates that all women in the study were at least 42 years old. It is therefore not certain whether the result of an AMH measurement can also be transferred to younger women. (vb)

Author and source information

This text corresponds to the specifications of the medical literature, medical guidelines and current studies and has been checked by medical doctors.

Graduate editor (FH) Volker Blasek


  • National Health Service (NHS): Could a new blood test predict when menopause will start? (Posted: 1/23/2020),
  • Joel S Finkelstein, Hang Lee, Arun Karlamangla, u.a .: Anti-Mullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation; in: Journal of Clinical Endocrinology and Metabolism (JCEM), 2020,

Video: Symptoms of Menopause: Beyond the Physical (October 2022).